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In contrast, in cells pre-treated for 60 min with BCNU prior to H 2 O 2 addition, we observed no NAPstar3b response at all, consistent with our observations of genetic disruption of glutathione reductase in yeast, plants, and HEK293 cells

Medicine 98:e16163

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In summary, we established a novel mouse model of parkinsonism based on the LRRK2.p.N1437D point mutation that exhibited behavioral and pathological damage and explored its pathological characteristics