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Acta Physiol Scand (1997) 159(4):3215

[260] [261] Since the total number of microbial and viral cells in the human body (over 100 trillion) greatly outnumbers human cells (tens of trillions), [note 21] [260] [262] there is considerable potential for interactions between drugs and an individual's microbiome, including: drugs altering the composition of the human microbiome, drug metabolism by microbial enzymes modifying the drug's pharmacokinetic profile, and microbial drug metabolism affecting a drug's clinical efficacy and toxicity profile

PT-141 is a melanocortin receptor agonist commonly discussed in research contexts around desire, arousal signalling, and sexual wellbeing pathways

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