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We report three major findings: (1) patients with FEP with higher GSH levels in ACC show a rapid symptom reduction upon starting antipsychotic treatment, (2) when compared with healthy controls, GSH levels in patients are dissociated from glutamate levels, and (3) Glutamate excess predicts the degree of Social and Occupational dysfunction seen at the time of presentation with FEP
We thank our participants and the coordinators of the University of Pittsburgh Asthma and Environmental Lung Health Institute at the University of Pittsburgh Medical Center for their patient recruitment and management
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