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Possible drug interactions include: Alcohol may increase the risk of lactic acidosis (Janumet) Carbonic anhydrase inhibitors such as topiramate, zonisamide, acetazolamide or dichlorphenamide may increase the risk of lactic acidosis (Janumet) Digoxin (Januvia) Insulin may increase the risk of low blood sugar (Januvia and Janumet) Share This Page: Who Am I Calling

doi: 10.1016/j.molmet.2020.101090 18

J.NealB.BompointS.HeerspinkH

In the work described here, the pharmaceutical formulation used to achieve oral delivery, Axcess- comprising a combination of chenodeoxycholate and propyl gallate as absorption enhancers, is one which has already been employed successfully in humans to achieve delivery of insulin in a safe, efficacious and commercially viable manner