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Mild vitamin B deficiencies can improve within weeks with proper supplementation, while severe cases may require months of consistent treatment, including injections or dietary changes

Notably, 98.3% of patients treated with adagrasib had already received immunotherapy and chemotherapy, so it is a new hope for these patient groups

Uric acid-mediated inflammasome activation in IL-6 primed innate immune cells is regulated by baricitinib

Future research and clinical trials will play a crucial role in optimizing the use of HDACi, elucidating resistance mechanisms, and identifying the most effective combinations to maximize patient benefit