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PGNI, as a targeted inhibitor, was shown to inhibit fatty acid synthesis by activating the AMPK pathway, thereby improving NAFLD, significantly advancing nanomaterial research for fatty liver disease treatment

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By altering Wnt pathway genes, ipafricept, a decoy receptor for Wnt ligands, has demonstrated potential in the treatment of solid cancers ( Through blocking the Wnt/-catenin signaling pathways, vitamin C has been found to promote bone regeneration ( 4.6 Liver and kidney functions and histopathological findings Approximately 30% of the LZD is excreted unchanged by the kidneys, while the rest is metabolized by oxidizing its morpholine ring, which is facilitated by ROS using NADPH in the liver ( The present study showed that linezolid-induced liver damage was demonstrated by an increase in the marker enzymes alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT)