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The clinical pictures of vitamin B12 allergy caused by type 1 hypersensitivity that have been revealed with basophile histamine release test and skin prick tests as we have performed in our patient.10 We did not perform basophile histamine release test or specific IgE determination to indicate type 1 hypersensitivity reaction because of positive SPT results of both types of cobalamin preparation

Yes, B 29 AQ 1500MCG PREFILLED SYRINGE(PFS) causes headache as it is the commonest side effect associated with the use of B 29 AQ 1500MCG PREFILLED SYRINGE(PFS)

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This makes B12 injections much more absorbable than an oral supplement