dulaglutide and semaglutide An indirect treatment comparison of the efficacy of 1.0 mg versus 3.0 4.5 mg Dulaglutide vs Semaglutide | A

So I dont think this aspect is a concern

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Several plausible pathways may explain the reduced pregnancy and birth outcomes observed with semaglutide pretreatment: 1

Excessive activation of the NMDA receptor causes powerful release of calcium ions, inducing excitotoxicity and, consequently, cell death (Ju and Cui 2016)