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While I neither condone nor take offense on using compounded products for off label, fda approved drugs are used or perscribed off label greater than 50% of the time

et al., Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH, N Engl J Med 2023;389:998-1008, DOI: 10.1056/NEJMoa2304286

(At the time of writing, the FDA still hasnt approved piracetam for use in supplements or as a prescription medication, though many still take it.)3 Nootropics also technically include prescription medications like Adderall (amphetamine salt), Vyvanse (lisdexamfetamine), and Ritalin (methylphenidate),62 as well as medications for dementia and Alzheimers disease (such as memantine).63 Caffeine is also a nootropic substance and an ingredient youll find in many nootropic supplements