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copri intervention, mediated through gut barrier repair, significantly restores bone homeostasisincluding enhanced bone density and bone remodeling balanceand promotes osteoblast ferroptosis resistance in both in vitro cellular models (e.g., MC3T3-E1 cultures) and in vivo animal models (e.g., OA mice) (Li et al., 2025)

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GLP-1 receptor agonists like Foundayo mimic this hormone at a sustained therapeutic level, reducing appetite, limiting calorie intake, and supporting long-term weight loss when combined with diet and exercise

Theres a rebound effect that goes far beyond weight and Al-Aly says that there is a danger that could put people at risk of cardiac events