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Introduction In addition to the ongoing opioid crisis, cocaine use disorder continues to present as a public health issue and for which there are currently no Food and Drug Administration-approved pharmacotherapies

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Because of its defined amino acid structure and reproducible synthesis profile, it is often included in controlled laboratory research evaluating peptide behavior, receptor binding characteristics, and analytical peptide performance

The ratio of target-receptor agonism can be manipulated to maximise efficacy whilst optimising adverse effects [31]