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Derivatization is a process by which a compound is chemically changed to a new compound that has properties suitable for a particular assay or particular analytical method and the agent that carries out this process is called a derivatizing agent

The label expansion follows the FDAs March 2025 approval of an expanded label for lutetium Lu-177 vipivotide tetraxetan (Pluvicto) for use in patients with metastatic castration-resistant prostate cancer after treatment with an androgen receptor pathway inhibitor and before chemotherapy

This tripeptide plays a crucial role in maintaining cellular health and protecting against oxidative stress

Its other major function is generation of superoxide (O 2 ) by NADPH oxidases (NOXs) and scavenging of H 2 O 2 by regenerating GSH and the antioxidant protein thioredoxin (TRX)