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These investigations primarily focus on understanding peptide-mediated signaling events associated with angiogenesis, cellular migration, cytoprotection, and extracellular matrix dynamics

Additional information Statement of Financial Support This study was enabled by funding from the Netherlands Organisation for Health Research and Development ZonMw (Grant number: 80-83600-98-10190)

This is known as "Macrophage Polarization." The ability to shift from M1 to M2 efficiently is the Holy Grail of wound repair

Although current data support the notion that HDACi overcomes resistance through epigenetic regulation and inhibition of pro-survival pathways, the limitations of small sample sizes and non-randomized designs necessitate validation through larger-scale studies (102)