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Mounjaro FDA Safety Label Change Ozempic (semaglutide) subcutaneous weekly injection FDA Approval Year: 2017 Ozempic FDA Safety Label Change Rybelsus (active ingredient: semaglutide) once-daily pills FDA Approval Year: 2019 Rybelsus FDA Safety Label Change Soliqua 100/33 (insulin glargine and lixisenatide) subcutaneous daily injection FDA Approval Year: 2016 Soliqua FDA Safety Label Change Trulicity (dulaglutide) subcutaneous weekly injection FDA Approval Year: 2014 Clinical trials reports of stomach problems (gastrointestinal effects) added

T.Delfino-PereiraP.Garcia-CairascoN.De Lima UmeokaE

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Patients carrying certain variants in genes related to glucose-dependent renal reabsorption may experience glucosuria (glucose in urine) at higher rates when on semaglutide, providing additional substrate for bacterial growth