These potential cardioprotective effects may be related to the favourable actions of metformin on lipid metabolism, vascular smooth muscle, hypercoagulation, platelet hyperactivity, cardiomyocyte intracellular calcium handling and endothelial function [24]
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If I were to play a note outside the key, say a G#, it would be called non-diatonic--meaning that the note is not diatonic, or does not belong, to the key of C major