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In soggetti con funzione renale fortemente compromessa o in dialisi, la somministrazione orale cronica di L-carnitina pu dare luogo ad accumulo di TMA e TMAO nel sangue con conseguente trimetilamminuria, condizione patologica caratterizzata da un forte "odore di pesce" presente nelle urine, nell'alito e nel sudore del paziente

BP lowering was consistent across a range of baseline BP levels and most subgroups with a safety profile typical of incretin-based therapies approved for chronic weight management

Called hypothyroidism , the condition is characterized by a low metabolic rate, weight gain, cold extremities, constipation, reduced libido, menstrual irregularities, and reduced mental activity

Substance use disorders are generating particularly compelling signals