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Through the December 19, 2021, data cutoff, a total of 1,075 subjects were randomized (1:1) to receive PAXLOVID or placebo orally every 12 hours for 5 days

8.3% of participants reported using them for four months

First, we restricted eligibility to primary studies published in peer-reviewed journals indexed in major international databases (e.g., Web of Science Core Collection and/or Scopus) and ranked within the top three quartiles (Q1Q3) of their subject category according to the most recent Journal Citation Reports (Clarivate Analytics, Philadelphia, PA, USA) or Scimago Journal Rank (Scimago Lab, Madrid, Spain) at the time of the search