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341 used exosomes derived from natural killer (NK) cells as a carrier of siRNA targeting BCL-2 to treat patients with estrogen receptor-positive (ER + ) breast cancer, resulting in enhanced apoptosis of breast cancer cells

In addition, the treated groups revealed significant upregulation of 7nAChRs at both gene and protein levels, resulting in improved brain damage [36]

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Downregulated microRNA-135a Ameliorates Rheumatoid Arthritis by Inactivation of the Phosphatidylinositol 3-Kinase/AKT Signaling Pathway via Phosphatidylinositol 3-Kinase Regulatory Subunit 2