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Administering AOD-9604 when these receptors are already occupied or downregulated produces suboptimal results regardless of dose

Changes in both gross clinical exam and microscopic structure of cartilage in the affected joints indicates that AOD9604 is effective in treating the root cause of osteoarthritis and may work as both a treatment and preventative

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The single-dose toxicity study revealed no test-related effects in the organs of treated animals, further supporting its safety