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This forces researchers to choose one pathway to study, leading to biased comparisons

These overlapped genes which are co-regulated by GSH, Glu, and wounding or independently regulated by GSH and wounding, Glu and wounding are all mainly involved in plant defense signaling, including plant response to wounding, stress, JA, and biotic stimulus, regulation of cell communication, and innate immune response, suggesting that GSH and Glu are involved in wound-induced plant systemic defense response

Although there is a high volume of studies supporting these conclusions, the overall certainty of evidence is moderate because there are very heterogeneous outcome measures across studies, variable factors that control body composition, and the duration of interventions is often relatively short