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More importantly, the hazard ratio for major adverse cardiovascular events (including cardiovascular death, myocardial infarction, stroke, or hospitalization for unstable angina) for the pooled tirzepatide groups versus glargine was 0.74 (95% CI 0.511.08), suggesting no increased cardiovascular risk with tirzepatide compared to insulin glargine

Hold the button down for 10 seconds, then gently remove the needle

GLP-1 receptor agonists may be appropriate second-line agents after metformin or even first-line in patients with established cardiovascular disease, chronic kidney disease, or when weight management is a priority