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To serve as mucoadhesive polymers, the polymers should possess some general physiochemical features such as predominantly anionic hydrophilicity with numerous hydrogen bond forming groups, suitable surface property for wetting mucus/mucosal tissue surfaces and sufficient flexibility to penetrate the mucus network

Runners knee is most common in middle aged women and people who are overweight

Moreover, rutin's ability to modulate inflammatory pathways, particularly by inhibiting the NLRP3 inflammasome and the NF-B signaling pathway, contributes to its protective effects in colitis (48, 49)

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