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The Neurological Assessment of Thioctic Acid in Diabetic Neuropathy trial (NATHAN), the longest and largest multicenter, randomised, double-blind, parallel-group trial in patients with uncontrolled diabetes and DPN, showed a favourable effect of a daily dose of 600 mg ALA orally for four years on neuropathic symptoms but not in conduction velocity

Keep in mind that STEP trials showed anxiety-related issues in just 1% or fewer participants

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Researchers study Retatrutide 5MG in preclinical and early research settings focused on metabolic signaling, energy balance, and glucose related pathways