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Afterward, before counterstaining with hematoxylin the specimens and cells were visualized until brown color with DAB kit (Thermo Scientific, USA) at dark condition

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Figure 5 Contrary to the results obtained after modification in the C-terminal of Ang IV where essentially all compounds examined exhibited some activity, oxidative cyclization of the side chains of Cys 1 and Cys 3 and consequently creation of an 11-membered disulfide macrocycle in the N-terminal rendered the inactive compound 20 (Figure 6)

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doi: 10.1016/j.eclinm.2021.101213 234 MaRDingXWangYDengYSunA

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