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10.1210/endo-127-5-2217 45 LeiS.ClydesdaleL.DaiA.CaiX.FengY.YangD.et al (2018)

Unregulated market: Since supplements are not FDA-approved, the actual ingredients and dosages may not match whats listed on the label

The absolute net benefit of attaining 10% weight loss without experiencing worrisome harms over 2 years was equivalent to 104 (95% CI, 100-112) per 1,000 people, Moll and colleagues reported

Over time, insulin exposure becomes prolonged and repetitive not because of overeating alone, but because the body has lost metabolic capacity

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