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Bone health after exercise alone, glp-1 receptor agonist treatment, or combination treatment: a secondary analysis of a randomized clinical trial

513,514 These signaling pathways suggest that GLP-1 and its receptor agonists may influence the progression of NASH through multiple mechanisms, providing several potential therapeutic targets including: FOXO1, a transcription factor that plays a critical role in regulating glucose and lipid metabolism

GLP-1 receptor agonists have been studied in PCOS, and reading across from that literature is the most defensible way to form a prior about what a more potent triple agonist might do

Others are looking into sourcing the medication from overseas, where safety standards could vary