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While these medications have redefined what is possible in weight management by reducing appetite and improving insulin sensitivity, their effectiveness can come with the unintended consequence of losing muscle mass if no structured plan is in place

Caution is still warranted

The annual cost of Trulicity, for example, is over $10,000, according to these data. The report concluded GLP-1s are not cost-effective at their current prices, and are largely unavailable to people with lower incomes. It is important for Rhode Islanders to get the care and medications they need to live the healthiest lives possible, but at prices that are not burdensome and a deterrent to access, the report states

Gastrointestinal Effects By far, gastrointestinal side effects like nausea, vomiting, diarrhea and constipation are the most common