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It contains no doses and makes no claim that any substance discussed is safe or effective for any use

It induces delta-wave sleep (NREM stage 3-4), the most restorative stage of sleep, by modulating circadian rhythms and the balance between inhibitory serotonin/GABA systems and activating pathways

Eric Topol of Scripps Research Translational Institute was more direct: "These peptides have no data to support their safety and efficacy." The clinical proponents argue that the FDA's safety concerns immunogenicity risk, impurity risk, organ toxicity are theoretically valid but speculative in practice