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But for many families, the bigger question becomes: What happens next

Once the affected intestine is removed, the two healthy ends of the intestine are joined back together (called anastomosis)

P2Y 2 receptor agonists, denufosol (OLIYNYK et al., 2010), were promising for their ability to activate alternative chloride secretion pathways, but both of these agonists have not been pursued further due to not meeting primary study goals of improving FEV 1 (Ratjen et al., 2012) and having a narrow effective concentration range, respectively (OLIYNYK et al., 2010)

HGF/c-Met receptor activation: Dihexa binds to and activates the hepatocyte growth factor (HGF) and c-Met receptor system, a powerful signaling pathway involved in cell growth, repair, and neurogenesis