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Nutritional and Lifestyle Guidance Medication alone is not a complete solution

In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation

Regular follow-up allows monitoring of both B12 levels and liver disease progression, with treatment adjustments as needed

Common digestive side effects include: Nausea (affecting up to 44% of patients in clinical trials) Diarrhoea (approximately 30% of patients) Constipation (around 24% of patients) Vomiting (reported by roughly 24% of patients) Abdominal pain, bloating, and dyspepsia Gastro-oesophageal reflux symptoms These effects are typically most pronounced during dose escalation and often improve as the body adapts to the medication