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We therefore considered the possibility that PUF-3 and PUF-11 also form partnerships with LST-1 and SYGL-1

However, the use of the PRIME T2D Model, which has demonstrated positive validation results against CVOTs (including LEADER) with no calibration required, could mitigate the absence of direct inclusion of CVOT data in the present study, and this represents a key strength of the PRIME T2D Model, particularly given the previously poor results of validation exercises across type 2 diabetes models [18, 51, 52]

Watch now To view or add a comment, sign in GLP1, Wegovy, has recently been FDA-approved for MASH patients with moderate-to-advanced fibrosis hot on the heels of last years approval of first-mover, Rezdifrra