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Additional risk factors encompass age, obesity (BMI 30), inadequate diet, alcohol consumption, anxiety and depression, working in extremely hot conditions, the presence of Cushings syndrome, mumps, hypospadias, anemia, diabetes, metabolic syndrome, and thyroid diseases (37, 38)

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Some common side effects include: Dry skin due to medication, reducing oil production Dry lips, mouth, and eyes Nasal dryness that can sometimes lead to mild nosebleeds Dry or thinning hair Muscle or joint aches Mild headaches Fatigue Mood changes Changes in liver and cholesterol levels Accutane is a medication that decreases oil production, so the most common side effect is dryness

Other GLP-1 agonist drugs for diabetes, including Mounjaro (tirzepatide), have similar benefits