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The purpose of this model was to study the properties of intracellular glutathione metabolism, in particular the effects of oxidative stress and trisomy 21

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Physcomitrella apparently lacks any chloroplastic isoform indicating that AsA reduction in the plant exclusively occurs in cytosol (Drew et al., In order to protect against the deleterious effects of ROS, the AsA pools are required to be maintained in a reduced state

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