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GLP-1 and GIP are incretin hormones that stimulate insulin secretion after an oral glucose load by binding GLP-1R, but both are rapidly inactivated by the enzyme dipeptidyl peptidase-4 (DPP-4)

At Flow Wellness, we frequently use: Extended time at each dose Half-step dose increases (or less sometimes!) Ultra-gradual transitions These allow your metabolism and digestive system to acclimate without unnecessary discomfort

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