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The takeaway from these studies: Obesity is a chronic condition and without ongoing treatment (whether medication, surgery, or intensive behavioral support), biology will try to pull weight back up

The strategy underscores mounting pressure on large multinationals to balance scale with agility in response to inflation-worn shoppers and fragmented eating habits

The frequency varies among clinical trials, although it usually ranges between 15 and 50% (Table 1)

The increment of insulin secretion in response to GLP-1 or GIP infusion during the hyperglycemic clamp study indicates the -cell incretin sensitivity [9-11]