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Additionally, studies evaluating the efficacy of Akt/mTOR activation as a possible latency reversing agent (LRA) have had little in vivo success ( Pharmacological derivatives of rapamycin, or rapalogs, that inhibit mTOR complexes include tacrolimus, sirolimus, and everolimus have been used in multiple clinical studies involving PLWH ( + T cells

The patch represents a way to get stable levels over time, without needing to take lots of supplements