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Pharmacological attempts to treat obesity have had limited success, with notable adverse effects, rendering bariatric surgery as the only current therapy for substantially improving body weight
Similarly, once the inducing agent is removed, the effects on hepatocytes may take a few weeks to resolve (time for the xenobiotic to be cleared and for enzymes to degrade)
L-carnitine is formed through the splitting-off of the acetyl group, which is responsible for the transport of long-chain fatty acids into the mitochondria, where it is utilized for the production of energy (ATP)
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