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Initial results from a randomized controlled trial indicated that it reduced weight and improved diabetic control
5 , e003960 (2016)
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Its downregulation has been shown to suppress the degradation of unsaturated fatty acids through multiple mechanisms, including inhibiting the activity of key enzymes involved in fatty acid catabolism (e.g., acetyl-CoA dehydrogenase, lipoxygenase, and fatty acid dioxygenase) and activating the PPAR signaling pathway and its downstream target genes [71]
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