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If mitochondria are not protected against OS insult, the organelles become irreversibly damaged through a process culminating with induction of a mitochondrial permeability transition (mPT) which is associated with the collapse of mitochondrial membrane () and colloid osmotic swelling of the matrix [46]

Ganey T, Hutton WC, Moseley T, Hedrick M, Meisel HJ: Intervertebral disc repair using adipose tissue-derived stem and regenerative cells: experiments in a canine model

Osteoarthritis Cartilage 7 , 377379 (1999)