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Summary: Rybelsus (semaglutide) is an oral GLP-1 receptor agonist that improves blood glucose control in adults with type 2 diabetes by stimulating insulin secretion, suppressing glucagon, and slowing gastric emptying

GLP-1RAs for ischemic stroke prevention in patients with type 2 diabetes without established atherosclerotic cardiovascular disease

Cell culture Primary human umbilical vein endothelial cells (HUVECs) (National Stem Cell Translational Resource Center, Shanghai, China, #DFSC-EC-01), Primary human Coronary Artery Endothelial Cells (HCAECs) (American Type Culture Collection, Manassas, VA, #PCS-100-020), and murine lung microvascular endothelial cells (MLMECs) were cultured in Endothelial Cell Medium (ECM) (Sciencell, Faraday Ave, Carlsbad, #1001)

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