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4 Zebrafish models for mechanistic insights into drug-induced liver injury and phytochemical protection Drug-induced liver injury (DILI) represents a significant clinical challenge, arising from the direct or indirect hepatocellular damage caused by pharmaceuticals or their metabolites (Andrade et al., 2019)

The increased expression of Cx32 in hepsin / mice seemed to exacerbate liver injury rather than having a cytoprotective effect in the context of APAP-induced liver injury

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