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PT-141 is evaluated in laboratory research for: Its melanocortin receptor activity differentiates it from incretin-based metabolic peptides and mitochondrial signaling compounds

Abbreviations 3D: Three-dimensional DARPin: Designed ankyrin repeat protein ECD: Extracellular domain GLP-1: Glucagon like peptide-1 GR: Gyration radius HSA: Human serum albumin MD: Molecular dynamics RMSD: Root mean square deviation RMSF: Root mean square fluctuation SASA: Solvent-accessible surface area T2DM: Type 2 diabetes mellitus References Piero, M., Nzaro, G

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