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Ayoub, [email protected] This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Based on Bell's findings, Holst and his colleagues knew that the sequence of human proglucagon was made up of 180 amino acids and that they had predicted that when translated it potentially cleaved into two peptides made up of 36 and 35 amino acids, respectively designated GLP-1 (1-36) and GLP-2 (rskov, Holst, Seier Poulsen, Kirkegaard

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