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Multiple cell types found in the enteroendocrine cell system, the pancreatic islets or the brain have been shown to express the GCG product, a 180 aminoacids long peptide known as proglucagon (PG) (106, 107), which gets trimmed tissue-dependently into at least 6 different bio-active peptides, namely glicentin, oxyntomodulin, glucagon, miniglucagon, GLP-1 and GLP-2 (108, 109)

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Myron Yaster MD Original article Pai SL, Nimma SR, Beam WB, VanderWielen BA, Kalagara HK, Bettini LM, Yu S, Sharpe EE, Harbell MW