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"Understanding who does well and who does not is a bit of a 'holy grail' question in weight-loss research, but nobody has the answer to that yet," Koutoukidis said

This ensures correct dosing, proper screening for contraindications, and monitoring of side effects

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Still, the SELECT trial does not mean every GLP-1 medication has the same cardiovascular outcome data, every patient qualifies for cardiovascular-risk reduction treatment, or GLP-1 therapy replaces standard heart-disease prevention