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We relied on the functional interplay between wild-type (WT) and mutant proteins to decouple the DNA- and RNA-dependent binding capability of Ubx and identified a new molecular mechanism by which Ubx regulates splicing through homodimerization

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( ( ( ( After review of the information provided by the applicant, we noted in the CY 2026 OPPS/ASC proposed rule that we have the following concerns regarding whether the Axoguard HA+ Nerve Protector TM meets the substantial clinical improvement criterion

This solution is designed for intramuscular or intravenous injection, typically administered using a syringe