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Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation
Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency
Hematocrit, reticulocyte count, vitamin B 12, folate and iron levels should be obtained prior to treatment
It is very hygroscopic in the anhydrous form, and sparingly soluble in water (1:80)
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