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Disturbances in glutamate-mediated neurotransmission have been increasingly documented in a range of neuropsychiatric disorders including schizophrenia, substance abuse, mood disorders, Alzheimer's disease, and autism-spectrum disorders

This substantial reduction in food noise with GLP1 RA drugs, when combined with behavioral treatment, is in line with previous anecdotal findings and may serve as an early indicator of treatment response. The team says this finding is important because food noise can make healthy behaviors much harder to maintain over time

By helping to regulate blood sugar levels, semaglutide also reduces appetite, making it easier to stick to a calorie-controlled diet

, Emmerson, P