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As a GHRH secretagogue that is subcutaneously injected, ipamorelin likely causes side effects related to frequent injections such as pain, rash or soreness at injection sites, in common with other forms of GH therapies [19]

Common and Systemic Side Effects Dermal/Pigmentation: General skin darkening (tanning), and crucially, the darkening and potential change in shape or size of pre-existing moles (nevi)

Moreover, studies were also included that combined caffeine and other bioactive compounds found in coffee, green tea, other beverages, food, and medicine

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